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Circle, the issuer of stablecoin USDC, has announced it will discontinue support for consumer Circle Mint accounts and no longer create new accounts for individual retail consumers. This move may benefit Tether, which will support individual consumer accounts but with a minimum limit of $100,000. Tether remains the largest stablecoin issuer with a total supply of around $91 billion for its USDT token, while Circle has a total supply of about $27 billion for USDC. Tether's third-quarter attestation report showed cash and equivalents accounted for 85.7% of its total reserves, the highest ever.

Portfolio Pulse from Khyathi Dalal

October 31, 2023 | 10:59 pm

CRSP

CRISPR Therapeutics has completed an FDA Advisory Committee meeting for Exagamglogene Autotemcel (exa-cel) for severe Sickle Cell Disease. The PDUFA target action date is December 8, 2023. If approved, exa-cel could be the first genetic therapy available to approximately twenty thousand people with severe SCD in the U.S. The Biologics License Application for transfusion-dependent beta-thalassemia was assigned a PDUFA date of March 30, 2024.

Portfolio Pulse from Benzinga Newsdesk

October 31, 2023 | 9:56 pm

LLY

NVO

The supply of diabetes drug Ozempic, also used for weight loss, is running low in the US. The shortage is affecting other similar drugs like Mounjaro from Eli Lilly And Co. The shortage has led to people ordering off-brand versions online, which can be dangerous. The shortage has also affected Calibrate, a telehealth company focused on weight-loss services, leading to its CEO stepping down.

Portfolio Pulse from Aaron Bry

October 31, 2023 | 9:23 pm

NVAX

Novavax has received approval from the European Union (EU) for its updated COVID-19 vaccine. The company is now working with EU member states to distribute the vaccine to those who have requested doses through the advance purchase agreement.

Portfolio Pulse from Benzinga Newsdesk

October 31, 2023 | 9:08 pm

AMD

Advanced Micro Devices (AMD) has announced that it will hold an AI event on December 6, 2023, to showcase its AI chip products, according to a conference call cited by Reuters.

Portfolio Pulse from Benzinga Newsdesk

October 31, 2023 | 9:05 pm

AAPL

AMZN

Apple Inc.'s 12.9-inch iPad Pro powered by the M2 chip is now available at a discounted price of $990 on Amazon, marking a new all-time low. The discount includes a flat $150 off and an additional $60 off for Amazon Visa card applicants. The iPad Pro 2022 features a 12.9-inch Liquid Retina XDR display, M2 chip, 8GB of RAM, 256GB of storage, and a triple camera setup.

Portfolio Pulse from Rounak Jain

October 31, 2023 | 9:05 pm

TNXP

Tonix Pharmaceuticals announced that its Phase 2 study of TNX-601 ER for the treatment of Major Depressive Disorder did not achieve statistical significance on the primary endpoint. As a result, the company is discontinuing the development of TNX-601 ER. However, Tonix expects topline data results in December 2023 for its Phase 2 study of TNX-1900 in chronic migraine and Phase 3 study of TNX-102 SL in fibromyalgia.

Portfolio Pulse from Benzinga Newsdesk

October 31, 2023 | 9:01 pm

CLLS

Cellectis has presented pre-clinical data on multi-armored allogeneic MUC1-CAR T-cells targeting triple-negative breast cancer at the Society for Immunotherapy of Cancer 38th Annual Meeting.

Portfolio Pulse from Benzinga Newsdesk

October 31, 2023 | 8:56 pm

NVS

The FDA has approved Novartis' Cosentyx for the treatment of moderate to severe Hidradenitis Suppurativa in adults. This approval could potentially increase Novartis' market share in the pharmaceutical industry.

Portfolio Pulse from Benzinga Newsdesk

October 31, 2023 | 8:55 pm

AURA

Aura Biosciences Inc. (NASDAQ:AURA) announced that updated data from the Phase 2 trial evaluating the safety and efficacy of its first virus-like drug conjugate (VDC) product candidate, bel-sar, for the first-line treatment of adult patients with early-stage choroidal melanoma will be presented at the American Academy of Ophthalmology (AAO) 2023 Annual Meeting. The meeting will be held from November 3-6, 2023, in San Francisco.

Portfolio Pulse from Benzinga Newsdesk

October 31, 2023 | 8:44 pm