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XPO

XPO Logistics, a leading provider of freight transportation in North America, reported preliminary LTL segment operating metrics for August 2023. The company saw a 3.1% YoY increase in LTL tonnage per day, due to an 8.1% increase in shipments per day and a 4.6% decrease in weight per shipment.

Portfolio Pulse from Happy Mohamed

September 05, 2023 | 8:24 pm

SIBN

SI-BONE, Inc. (NASDAQ:SIBN) has confirmed that certain CD Horizon Solera 5.5mm and 6.0mm posterior spinal fixation rods manufactured by Medtronic Sofamor Danek USA Inc., a division of Medtronic plc, are compatible with SI-BONE's iFuse Bedrock Granite implant. The Granite implant was cleared by FDA on May 26, 2022, and was designated as a Breakthrough Device due to its significant advantages over existing approved or cleared alternatives.

Portfolio Pulse from Happy Mohamed

September 05, 2023 | 8:22 pm

ACRV

Acrivon Therapeutics has announced the development of ACR-2316, a novel dual WEE1 and PKMYT1 inhibitor, using its proprietary AP3 platform. The company plans to submit an Investigational New Drug (IND) application for ACR-2316 by Q4 2024. The AP3 platform has been instrumental in the rapid generation of this novel dual inhibitor, which is optimized to potentially overcome resistance mechanisms induced by WEE1 and PKMYT1 single inhibitors.

Portfolio Pulse from Happy Mohamed

September 05, 2023 | 8:21 pm

NXTC

NextCure, Inc. (NASDAQ:NXTC) has presented preclinical data showing that its novel anti-Siglec-15 (S15) antibody, NC605, can reduce bone loss and enhance bone formation and quality in an animal model of acute spinal cord injury. Unlike anti-resorptive therapies, NC605 enhances osteoblast recruitment, resulting in overall enhanced bone quality. The data were presented at the 2023 Military Health System Research Symposium.

Portfolio Pulse from Happy Mohamed

September 05, 2023 | 8:21 pm

MRIN

Marin Software has announced its integration with HubSpot, a leading customer relationship management (CRM) platform. This integration will allow marketers to manage and measure search, social, and eCommerce advertising campaigns in one place.

Portfolio Pulse from Benzinga Newsdesk

September 05, 2023 | 8:20 pm

MLYS

Mineralys Therapeutics, Inc. (NASDAQ:MLYS) has been selected to present the full results from the Target-HTN Phase 2 trial of lorundrostat in individuals with uncontrolled hypertension or resistant hypertension at the 2023 American Heart Association Hypertension Scientific Sessions. Lorundrostat is a proprietary, orally administered, highly selective aldosterone synthase inhibitor being developed for the treatment of uncontrolled hypertension and CKD.

Portfolio Pulse from Happy Mohamed

September 05, 2023 | 8:09 pm

ASND

Ascendis Pharma A/S (NASDAQ:ASND) announced a new post hoc analysis showing that adults with hypoparathyroidism treated with TransCon PTH demonstrated substantial improvement in estimated glomerular filtration rate (eGFR), suggesting improved kidney function. Approximately 50% of Phase 3 PaTHway Trial patients with eGFR < 60 mL/min/1.73m2, the threshold for kidney dysfunction, receiving TransCon PTH experienced eGFR improvement to above 60 mL/min/1.73m2.

Portfolio Pulse from Happy Mohamed

September 05, 2023 | 8:02 pm

CMCSA

President Joe Biden's campaign plans to air a new advertisement during the first game of the 2023 NFL season. The ad, part of a $25 million campaign, will focus on Biden's economic record and will air during the Detroit Lions and Kansas City Chiefs game, broadcast on Comcast Corporation's NBC and Peacock. The ad will also air in several swing states.

Portfolio Pulse from Chris Katje

September 05, 2023 | 7:38 pm

NTDOY

Nintendo Company Ltd's (OTC:NTDOY) Nintendo Switch console continues to see success, with a 13.9% increase in sales in the June quarter. The success is attributed to the Super Mario Bros. Movie and exclusive games like The Legend of Zelda. Despite rumors of a new console, the company is focusing on maintaining the Switch's momentum. Nintendo's goal is to bolster demand for the upcoming holiday season.

Portfolio Pulse from Franca Quarneti

September 05, 2023 | 7:17 pm

AFRM

Mizuho analyst Dan Dolev has maintained a Buy rating for Affirm Holdings Inc (NASDAQ:AFRM) and raised the price target from $20 to $25. Dolev is encouraged by the early results of the Affirm Card and sees potential for growth as the card is adopted by more of AFRM's 16.5 million customers. He has raised FY24 and FY25 revenue and adjusted operating income estimates based on 4Q results and management's fresh guidance. Despite potential negative catalysts, Dolev remains bullish on AFRM's prospects.

Portfolio Pulse from Anusuya Lahiri

September 05, 2023 | 7:13 pm