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LLY

The FDA granted conditional approval for Eli Lilly's Jaypirca for treating adult patients with chronic lymphocytic leukemia or small lymphocytic lymphoma who have undergone at least two prior therapies. The approval, under the FDA's Accelerated Approval pathway, was based on the Phase 1/2 BRUIN trial results, which showed a 72% overall response rate. Jaypirca is the first FDA-approved non-covalent BTK inhibitor and comes with specific warnings and precautions. This follows a previous approval in January 2023 for a different indication.

Portfolio Pulse from Vandana Singh

December 04, 2023 | 12:06 pm

ETNB

89bio has announced alignment with the FDA and EMA on a Phase 3 program for Pegozafermin, a treatment for Nonalcoholic Steatohepatitis (NASH). The program is set to begin in the first half of 2024.

Portfolio Pulse from Benzinga Newsdesk

December 04, 2023 | 12:05 pm

LLY

NVO

RHHBY

Roche Holding AG (OTC:RHHBY) is set to acquire Carmot Therapeutics to enter the competitive weight loss drug market, challenging Novo Nordisk (NYSE:NVO) and Eli Lilly (NYSE:LLY). Carmot's portfolio includes several incretin-based treatments for obesity and type 2 diabetes, with the lead asset CT-388 ready for Phase-2 trials. Roche will pay $2.7 billion in cash plus up to $400 million in milestone payments. The acquisition will also give Roche access to Carmot's discovery platform, enhancing its R&D in metabolism-related diseases. The deal is expected to close in Q1 2024.

Portfolio Pulse from Vandana Singh

December 04, 2023 | 12:04 pm

APLM

Apollomics has presented efficacy and safety data from the ongoing KUNPENG and SPARTA trials of Vebreltinib at the IASLC North America Conference on Lung Cancer. The data is significant for the continued development and potential future approval of Vebreltinib for treating lung cancer.

Portfolio Pulse from Benzinga Newsdesk

December 04, 2023 | 12:04 pm

BABA

FXI

PDD

Alibaba Group Holding Limited (NYSE:BABA) stock is trading lower, in line with the broader IShares China Large-Cap ETF (NYSE:FXI). Alibaba lost its title as China's most valuable e-commerce company to PDD Holdings Inc (NASDAQ:PDD). BABA's stock is down 20% YTD, while PDD's stock is up 72%. Alibaba Cloud has open-sourced large language models, including a 72-billion-parameter model and a 1.8-billion-parameter model, and introduced new multimodal LLMs. BABA shares traded lower by 1.54% at $72.84 in premarket trading.

Portfolio Pulse from Anusuya Lahiri

December 04, 2023 | 12:01 pm

ABSI

AZN

NVDA

RHHBY

AstraZeneca plc (NASDAQ:AZN) has entered into a partnership with Absci Corporation (NASDAQ:ABSI) to develop an AI-driven antibody for cancer treatment, with a deal value of up to $247 million. Absci will receive an upfront fee, R&D funding, milestone payments, and royalties on product sales. The collaboration aims to leverage Absci's AI technology for protein analysis to accelerate drug discovery. This move is part of a broader trend of incorporating AI into pharmaceutical research, as seen with Genentech's recent partnership with NVIDIA Corporation (NASDAQ:NVDA). ABSI stock rose 8.62% in premarket trading.

Portfolio Pulse from Vandana Singh

December 04, 2023 | 11:58 am

AAPL

Verizon Communications Inc. is offering a deal where customers can get an Apple Inc. iPhone 15 Pro, iPad (9th generation), and Apple Watch Series 8 for free, a package valued at $1,900. The deal includes a trade-in discount of up to $1,000, applied as a deduction on monthly mobile bills over 36 months. The iPhone 15 Pro features an A17 Pro chipset, a 6.1-inch Super Retina XDR OLED display, a titanium alloy design, a triple camera setup with a 48MP primary camera, and the new USB-C port.

Portfolio Pulse from Rounak Jain

December 04, 2023 | 11:56 am

ASXC

Asensus Surgical has sold a Senhance Surgical System to its distribution partner, which will be placed in a hospital in the Commonwealth of Independent States (CIS) region. This sale marks the second system sold to the CIS region in the past month.

Portfolio Pulse from Benzinga Newsdesk

December 04, 2023 | 11:56 am

MSFT

NVEI

NYAX

Nuvei Corp has partnered with Microsoft to enhance payment experiences for Microsoft's products and services in the Middle East and Africa. The collaboration will leverage Nuvei's payment technology to improve authorization rates and risk management, and offer local payment methods through a single integration. Nuvei also recently launched a card-issuing solution in 30 markets and partnered with Nayax Ltd for payment solutions. Nuvei's stock (NVEI) closed up 3.21% at $21.19.

Portfolio Pulse from Lekha Gupta

December 04, 2023 | 11:34 am

AULT

Ault Alliance, Inc. announced that its subsidiary, Sentinum, Inc., is set to launch a new data center in Montana by January 2024. This move aims to enhance the company's Bitcoin mining operations by transitioning miners from a third-party hosted facility to its own data center, thereby improving profitability and efficiency.

Portfolio Pulse from Benzinga Newsdesk

December 04, 2023 | 11:31 am