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RIO

Rio Tinto (NYSE:RIO) is investing $143 million in a new research and development facility in Western Australia to advance low-emission steelmaking technology. The facility will focus on the BioIron™ process, which uses biomass instead of coal, potentially reducing CO2 emissions by 95%. The project will create jobs and support collaboration with local universities.

Portfolio Pulse from Stjepan Kalinic

June 04, 2024 | 11:07 am

SPRB

Spruce Biosciences and HMNC Brain Health are collaborating to develop Spruce's investigational product candidate, Tildacerfont, with HMNC's companion diagnostic for Major Depressive Disorder. HMNC will initiate a Phase 2 study in Q4 2024.

Portfolio Pulse from Benzinga Newsdesk

June 04, 2024 | 11:05 am

ANNX

Annexon announced that its drug ANX005 at 75 mg/kg outperformed placebo on multiple endpoints in a clinical trial, but did not achieve statistical significance on the primary endpoint of GBS-DS at week 8.

Portfolio Pulse from Benzinga Newsdesk

June 04, 2024 | 11:03 am

NNVC

NanoViricides reported that its lead antiviral agent NV-387 showed a desirable blood concentration profile in a non-human primate model, maintaining a stable concentration over 24 hours with a dose-dependent increase.

Portfolio Pulse from Benzinga Newsdesk

June 04, 2024 | 11:03 am

SPRB

Spruce Biosciences Inc. (NASDAQ:SPRB) has entered into a collaboration with HMNC Brain Health GmbH to develop tildacerfont, an investigational product candidate, and HMNC's Cortibon Genetic Selection Tool for treating major depressive disorder (MDD). The collaboration includes a Phase 2 proof-of-concept study funded by HMNC, with Spruce having the option to in-license exclusive worldwide rights to Cortibon if the study results are positive.

Portfolio Pulse from Vandana Singh

June 04, 2024 | 11:02 am

ANNX

Annexon shares are trading higher after the company's Phase 3 trial of ANX005 met its primary endpoint.

Portfolio Pulse from Benzinga Newsdesk

June 04, 2024 | 11:02 am

ALLE

Allegion has acquired Krieger Specialty Products LLC, a manufacturer of special purpose doors and windows for industrial, commercial, and institutional markets. The terms of the deal were not disclosed. Krieger will operate under the Allegion Americas segment.

Portfolio Pulse from Benzinga Newsdesk

June 04, 2024 | 11:01 am

ANNX

Annexon announced that its Phase 3 ANX005 trial in Guillain-Barré Syndrome met its primary endpoint, indicating positive results for the treatment.

Portfolio Pulse from Benzinga Newsdesk

June 04, 2024 | 11:00 am

TM

Toyota Motor Corp (NYSE:TM) is recalling over 100,000 vehicles in the U.S. due to concerns about engine debris that could cause stalling and loss of driving power. The recall affects 2022-2023 Tundra and Lexus LX600 models. This comes amid other quality control issues for Toyota, including suspensions of shipments and sales of certain models in Japan.

Portfolio Pulse from Anan Ashraf

June 04, 2024 | 10:58 am

NIO

TSLA

NIO Inc. (NYSE:NIO) is undergoing an organizational reshuffle, rebranding its strategic new business units and maintaining existing department heads. The company also reported record EV sales in May. NIO's sub-brand Onvo has established 16 regional companies to advance its brand and sales. NIO shares are trading lower in the premarket session.

Portfolio Pulse from Nabaparna Bhattacharya

June 04, 2024 | 10:57 am