Denali: Despite ALS Primary Endpoint Failure, Possible Path Forward Remains
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Denali Therapeutics' DNL343 failed to meet the primary endpoint in the ALS trial, but potential biomarker analyses in 2025 may offer a path forward. The stock remains stable due to continued analyses and a BLA filing for tividenofusp alfa in early 2025.

January 09, 2025 | 9:15 pm
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Denali Therapeutics' DNL343 failed in the ALS trial, but potential biomarker analyses in 2025 may offer a path forward. The stock remains stable due to continued analyses and a BLA filing for tividenofusp alfa in early 2025.
Despite the failure of DNL343 in the ALS trial, Denali's stock remains stable due to the potential for future biomarker analyses and the upcoming BLA filing for another drug. This suggests that investors are maintaining confidence in the company's pipeline.
CONFIDENCE 90
IMPORTANCE 80
RELEVANCE 100