Roche's Phase IIb study of prasinezumab missed primary endpoint, but suggests possible benefit in early-stage Parkinson's disease
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Roche's Phase IIb study of prasinezumab for early-stage Parkinson's disease did not meet its primary endpoint but showed potential benefits, especially in patients treated with levodopa. The drug was well tolerated with no new safety concerns.
December 19, 2024 | 6:15 am
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Roche's Phase IIb study of prasinezumab did not achieve statistical significance in its primary endpoint but showed potential benefits in early-stage Parkinson's patients, particularly those on levodopa. The drug was well tolerated with no new safety issues.
The study results are mixed; while the primary endpoint was not met, there are positive indications in a subset of patients. This could lead to cautious optimism among investors, but the lack of statistical significance tempers immediate positive impact on stock price.
CONFIDENCE 90
IMPORTANCE 70
RELEVANCE 80