Vaccinex Reports New Findings For SIGNAL-AD Phase 1b/2 Trial Of Pepinemab At Clinical Trials On Alzheimer's Disease Conference In Madrid, Spain; Reports That Expression Of Plasma GFAP And Pp-tau 217 Biomarkers Appears To Increase Predominantly During MCI And That This Is Inhibited By Pepinemab Treatment
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Vaccinex reported positive findings from its SIGNAL-AD Phase 1b/2 trial of pepinemab for Alzheimer's disease, showing that the treatment inhibits biomarkers associated with disease progression. The study suggests pepinemab may slow cognitive decline in early stages of Alzheimer's.
October 31, 2024 | 2:02 pm
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Vaccinex's SIGNAL-AD trial results indicate that pepinemab inhibits biomarkers associated with Alzheimer's progression, potentially slowing cognitive decline in early stages. This could position pepinemab as a promising treatment option, differentiating it from current therapies.
The trial results are significant as they demonstrate pepinemab's potential to inhibit biomarkers like GFAP and p-tau 217, which are associated with Alzheimer's progression. This positions pepinemab as a potentially more effective treatment compared to current options, which may modestly slow cognitive decline. The absence of adverse effects related to vascular integrity further supports the positive outlook for pepinemab, likely leading to increased investor interest and a positive impact on Vaccinex's stock price.
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