Daiichi Sankyo And AstraZeneca Launch Three Phase 3 Trials For Datopotamab Deruxtecan-Based Combinations In Advanced Nonsquamous NSCLC; TROPION-Lung10, Lung14, And Lung15 Studies Target High PD-L1 Expression And EGFR Mutations With First Patients Dosed
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Daiichi Sankyo and AstraZeneca have initiated three Phase 3 trials for Datopotamab Deruxtecan-based combinations in advanced nonsquamous NSCLC. The studies, named TROPION-Lung10, Lung14, and Lung15, focus on high PD-L1 expression and EGFR mutations, with the first patients already dosed.

October 30, 2024 | 12:03 pm
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AstraZeneca, in partnership with Daiichi Sankyo, has launched three Phase 3 trials for Datopotamab Deruxtecan in advanced nonsquamous NSCLC, targeting high PD-L1 expression and EGFR mutations.
The initiation of Phase 3 trials is a significant step in drug development, indicating potential future revenue streams if successful. The focus on high PD-L1 expression and EGFR mutations targets a specific patient group, which could lead to a competitive advantage in the NSCLC treatment market.
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