Fulcrum Therapeutics Suspends Rare Muscular Disease Candidate After Disappointing Data From Pivotal Trial
Portfolio Pulse from Vandana Singh
Fulcrum Therapeutics Inc. (NASDAQ:FULC) announced disappointing results from its Phase 3 REACH trial for losmapimod in treating Facioscapulohumeral Muscular Dystrophy (FSHD). The trial did not meet its primary or secondary endpoints, leading the company to suspend the losmapimod program. Fulcrum plans to focus on other therapeutic programs, including treatments for sickle cell disease and Diamond-Blackfan Anemia. Following the news, FULC stock dropped by 59.30%.
September 12, 2024 | 3:32 pm
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NEGATIVE IMPACT
Fulcrum Therapeutics' stock plummeted 59.30% after the Phase 3 trial for losmapimod failed to meet primary and secondary endpoints. The company is suspending the losmapimod program and will focus on other therapeutic areas.
The failure of the Phase 3 trial for losmapimod, a key drug candidate, directly impacts Fulcrum's stock, causing a significant drop. The suspension of the program indicates a strategic shift, affecting investor sentiment negatively.
CONFIDENCE 100
IMPORTANCE 90
RELEVANCE 100