Ultragenyx, Mereo Report 14-Month Results From Phase 2 Portion Of Phase 2/3 Orbit Study; Treatment With Setrusumab Resulted In Sustained 67% Reduction In Annualized Fracture Rate In Osteogenesis Imperfecta Patients
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Ultragenyx and Mereo reported positive 14-month results from the Phase 2 portion of their Phase 2/3 Orbit study. Treatment with setrusumab (UX143) resulted in a sustained 67% reduction in the annualized fracture rate in osteogenesis imperfecta (OI) patients and significant improvements in lumbar spine bone mineral density (BMD) at month 12.

June 11, 2024 | 9:53 pm
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Mereo reported positive 14-month results for setrusumab in OI patients, showing a 67% reduction in fracture rate and improved BMD.
The positive results from the Phase 2 portion of the Phase 2/3 Orbit study are likely to boost investor confidence in Mereo, potentially driving the stock price up in the short term.
CONFIDENCE 90
IMPORTANCE 90
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POSITIVE IMPACT
Ultragenyx reported positive 14-month results for setrusumab in OI patients, showing a 67% reduction in fracture rate and improved BMD.
The positive results from the Phase 2 portion of the Phase 2/3 Orbit study are likely to boost investor confidence in Ultragenyx, potentially driving the stock price up in the short term.
CONFIDENCE 90
IMPORTANCE 90
RELEVANCE 100