Infection-Focused Barinthus Bio's VTP-200 Data Underwhelming: Analyst Weighs On Mixed Perspectives
Portfolio Pulse from Vandana Singh
Barinthus Biotherapeutics plc (NASDAQ:BRNS), previously known as Vaccitech plc, reported final topline results from the APOLLO trial of VTP-200 for low-grade cervical lesions associated with persistent hrHPV infection. The trial met its primary safety endpoint but showed no significant improvement in hrHPV or cervical lesion clearance rates in the overall pooled results, despite positive trends in higher dose cohorts. The company is evaluating future development options for VTP-200, while attention may shift to VTP-300 for chronic hepatitis B. BRNS shares dropped 5.90% to $2.71.
April 19, 2024 | 3:49 pm
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Barinthus Biotherapeutics reported mixed results from the APOLLO trial of VTP-200, showing safety but no significant efficacy, leading to a 5.90% drop in shares to $2.71.
The lack of significant improvement in efficacy outcomes for VTP-200, despite meeting safety endpoints, likely disappointed investors, leading to a decrease in BRNS stock price. The market's reaction reflects concerns over the future potential and development path of VTP-200, impacting investor sentiment and stock performance in the short term.
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IMPORTANCE 90
RELEVANCE 100