AstraZeneca's Imfinzi/Chemo Combo Doubles Overall Survival In Biliary Tract Cancer Patients At 3 Years, Data Shows
Portfolio Pulse from Vandana Singh
AstraZeneca Plc (NASDAQ:AZN) released updated results from the TOPAZ-1 Phase 3 trial of Imfinzi in combination with chemotherapy for advanced biliary tract cancer, showing significant survival benefits at three years. The data revealed a 26% reduction in the risk of death and more than double the survival rate at three years compared to chemotherapy alone. The trial met its primary endpoint of overall survival in October 2021.
April 16, 2024 | 12:53 pm
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AstraZeneca's Imfinzi, combined with chemotherapy, demonstrated significant long-term survival benefits in advanced biliary tract cancer, potentially boosting the company's oncology portfolio.
The positive results from the TOPAZ-1 Phase 3 trial of Imfinzi in advanced biliary tract cancer could enhance AstraZeneca's reputation in oncology and potentially lead to increased usage and sales of Imfinzi. This is particularly significant given the historical poor prognosis for this cancer type, indicating a strong potential for market impact. However, the slight premarket stock movement suggests that the immediate market reaction may be muted, possibly due to prior anticipation of these results or broader market conditions.
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