The IPO of NEONC TECHNOLOGIES HOLDINGS, INC is significant due to its focus on developing innovative cancer treatments. The specified price range and the insider lock-up period suggest a strong market entry strategy, potentially leading to a positive short-term impact on its stock price. The relevance of this news to NTHI is direct as it pertains to its market debut. The importance is high given the potential market response to new entries in the biotech sector, especially those involved in cancer research. The confidence level is set considering the general unpredictability of IPO performances but balanced by the promising sector of biotech.