Given 2seventy bio's mixed history of beating and missing EPS estimates and the significant year-to-date stock price decline, the upcoming earnings report could maintain the current stock price level or induce minor fluctuations. The anticipation of the earnings report and the company's guidance for future quarters are crucial factors that investors will closely monitor. However, the stock's recent performance suggests a cautious outlook among investors, which might limit the potential for a significant short-term price movement.