The increase in short interest for Anavex Life Sciences suggests that investors are more bearish on the stock. However, the impact on the stock price is uncertain in the short term, as high short interest can also lead to a short squeeze if the stock price were to rise unexpectedly. The relevance is high as the news is directly about AVXL's stock, but the importance is moderate because short interest is just one of many factors that can affect stock prices. The confidence level is not at the maximum because market sentiment can be unpredictable and does not always correlate with immediate price movements.