Why Applied Therapeutics Shares Are Trading Lower By Over 35%? Here Are Other Stocks Moving In Friday's Mid-Day Session
Portfolio Pulse from Avi Kapoor
Applied Therapeutics, Inc. (NASDAQ:APLT) shares plummeted by over 35% after announcing topline results from the ARISE-HF Phase 3 trial of AT-001, which did not meet its primary endpoint. Other stocks experienced significant movement in Friday's mid-day session, with various companies reporting gains due to positive updates, acquisitions, and earnings, while some faced declines due to negative guidance, downgrades, and public offerings.

January 05, 2024 | 6:13 pm
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NEGATIVE IMPACT
agilon health, inc. (NYSE:AGL) shares tumbled after the company lowered its 2023 financial outlook.
Downward revisions of financial outlooks can lead to a loss of investor confidence and a decline in stock price as future earnings potential is perceived to be lower.
CONFIDENCE 85
IMPORTANCE 85
RELEVANCE 90
NEGATIVE IMPACT
AngioDynamics, Inc. (NASDAQ:ANGO) shares declined after the company lowered its FY24 guidance.
Lowering future guidance often results in stock price decline due to anticipated weaker financial performance.
CONFIDENCE 85
IMPORTANCE 80
RELEVANCE 90
NEGATIVE IMPACT
Applied Therapeutics' stock plunged after Phase 3 trial results of AT-001 for Diabetic Cardiomyopathy were released, not meeting the primary endpoint.
Clinical trial results are critical for biotech companies. Failure to meet primary endpoints usually results in a significant negative impact on stock prices due to reduced confidence in the company's pipeline.
CONFIDENCE 90
IMPORTANCE 90
RELEVANCE 100
NEGATIVE IMPACT
Medical Properties Trust, Inc. (NYSE:MPW) fell after announcing plans to reduce exposure to tenant Steward Health Care System and a downgrade by Keybanc.
Reducing exposure to a major tenant and a downgrade by analysts can both negatively affect a stock, as they may signal concerns about the company's revenue and stability.
CONFIDENCE 85
IMPORTANCE 85
RELEVANCE 90
POSITIVE IMPACT
Elanco Animal Health Incorporated (NYSE:ELAN) gained after an upgrade from Hold to Buy by Stifel analyst Jonathan Block, with a raised price target.
Analyst upgrades and raised price targets can lead to increased investor confidence and a rise in stock price.
CONFIDENCE 80
IMPORTANCE 75
RELEVANCE 80