The filing of a new patent application by Tiziana Life Sciences for a combination therapy is a positive development, indicating progress in its research and potential expansion of its product pipeline. This could be seen favorably by investors, as it suggests the company is actively working on innovative treatments that could have a significant impact on a large market like obesity-related treatments. The news is directly related to Tiziana Life Sciences and is likely to have a positive short-term impact on the company's stock price.