Wave Life Sciences Announces Initiation Of Dosing In RestorAAtion Clinical Program Evaluating WVE-006, For Alpha-1 Antitrypsin Deficiency
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Wave Life Sciences has begun dosing in its RestorAAtion clinical program for WVE-006, a treatment for Alpha-1 Antitrypsin Deficiency (AATD). WVE-006 aims to correct the RNA mutation responsible for AATD, potentially addressing both lung and liver disease aspects. Wave received a $20 million milestone payment from GSK upon dosing initiation and could receive up to $505 million in additional milestones. Proof-of-mechanism data is expected in 2024. Wave is also developing other RNA editing therapeutics.

December 06, 2023 | 9:10 pm
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Wave Life Sciences has initiated dosing for WVE-006, targeting AATD, with a $20 million milestone payment from GSK and significant future milestone potential.
The initiation of dosing represents a significant development milestone for Wave Life Sciences, triggering a $20 million payment from GSK. This event not only provides immediate financial benefits but also validates the potential of WVE-006. The anticipation of future milestone payments could generate positive investor sentiment, potentially leading to a short-term increase in the stock price.
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