Weight Loss Drugs And Associated Suicidal Thoughts - European Drug Regulator Seeks Clarifications From Drug Makers
Portfolio Pulse from Vandana Singh
The European Medicines Agency (EMA) is seeking further clarifications from makers of GLP-1 receptor agonists, including Novo Nordisk's Ozempic and Wegovy, to investigate reports of suicidal thoughts. The PRAC has reviewed evidence from various sources and will discuss the issue in April 2024. Reports of suicidal ideation linked to these drugs, including cases from Iceland and off-label prescriptions in the U.S., have prompted this action. Companies affected include Novo Nordisk, AstraZeneca, Sanofi, and Eli Lilly.
December 01, 2023 | 5:43 pm
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NEGATIVE IMPACT
AstraZeneca's Byetta and Bydureon are part of the EMA's request for further clarifications on GLP-1 receptor agonists, which could lead to regulatory challenges and impact the company's drug portfolio.
AstraZeneca could face short-term negative impact on its stock due to the EMA's investigation into its GLP-1 receptor agonists, Byetta and Bydureon, as this could result in regulatory challenges and affect the perception of its diabetes and weight loss drug portfolio.
CONFIDENCE 70
IMPORTANCE 60
RELEVANCE 70
NEGATIVE IMPACT
Eli Lilly's Trulicity is part of the EMA's review of GLP-1 receptor agonists for potential mental health side effects, which could lead to regulatory scrutiny and affect the company's stock.
Eli Lilly could experience a short-term negative impact on its stock due to the EMA's investigation into Trulicity for potential links to suicidal thoughts, which may result in regulatory challenges and affect the company's reputation and sales of its diabetes and weight loss treatments.
CONFIDENCE 70
IMPORTANCE 60
RELEVANCE 70
NEGATIVE IMPACT
Novo Nordisk's drugs Ozempic, Wegovy, Rybelsus, Saxenda, Victoza, and Xultophy are under EMA's scrutiny for potential links to suicidal thoughts, which could impact the company's reputation and sales.
The investigation by EMA into Novo Nordisk's products for potential mental health side effects could lead to increased regulatory scrutiny, potential legal challenges, and a negative impact on the company's stock in the short term due to concerns over sales and reputation.
CONFIDENCE 75
IMPORTANCE 80
RELEVANCE 90
NEGATIVE IMPACT
Sanofi's Lyxumia and Suliqua are under investigation by the EMA for potential links to suicidal thoughts, which may lead to regulatory scrutiny and impact the company's stock performance.
Sanofi's inclusion in the EMA's request for clarifications regarding GLP-1 receptor agonists could negatively affect its stock in the short term due to potential regulatory challenges and concerns over the safety profile of its drugs Lyxumia and Suliqua.
CONFIDENCE 70
IMPORTANCE 60
RELEVANCE 70