Cancer Discovery Publishes Preclinical And Initial Clinical Data For MRTX1719 To Treat MTAP-Deleted Cancers through Novel Approach To MTA-Cooperative PRMT5 Inhibition
Portfolio Pulse from Happy Mohamed
Mirati Therapeutics, Inc. (NASDAQ:MRTX) announced that Cancer Discovery published preclinical and initial clinical data from a Phase 1/2 clinical trial of MRTX1719, a PRMT5 / MTA-cooperative inhibitor evaluated in MTAP deleted cancers. The results demonstrate that MRTX1719 may represent a promising targeted therapy for the ~10% of cancer patients with this biomarker. In preclinical studies, MRTX1719 showed marked anti-tumor activity across various solid tumor models. The drug was well-tolerated with no dose limiting toxicities observed.
August 09, 2023 | 8:37 pm
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Mirati Therapeutics' MRTX1719 shows promise in treating MTAP deleted cancers, potentially opening a new market for the company. The drug's positive preclinical and initial clinical results could boost investor confidence.
The positive results from the Phase 1/2 clinical trial of MRTX1719 could potentially open a new market for Mirati Therapeutics, as the drug targets a specific biomarker present in ~10% of cancer patients. This could lead to increased investor confidence in the company's ability to develop effective cancer treatments, potentially driving up the stock price in the short term.
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