How Venomous Lizard Played Crucial Role In Development Of Weight Loss Drug Ozempic
Portfolio Pulse from Benzinga Newsbot
Dr. Daniel Drucker discovered a hormone, GLP-1, which regulates blood sugar levels and suppresses appetite, leading to the development of diabetes drugs such as Novo Nordisk's Ozempic and Wegovy. The challenge was that GLP-1 quickly disappears from the human body, but a solution was found in the venom of the Gila monster, a venomous lizard. The venom contains a hormone, Exendin-4, which shares structural similarities with GLP-1 but does not break down quickly, making it an ideal candidate for a diabetes drug. This led to the development of Exenatide, the first approved treatment for Type 2 diabetes in 2005, and later, Ozempic.

June 29, 2023 | 8:42 am
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Novo Nordisk's Ozempic, a diabetes drug, was developed based on Dr. Daniel Drucker's discovery of the GLP-1 hormone. The venom of the Gila monster played a crucial role in this development.
The news highlights the unique development process of Novo Nordisk's Ozempic, which could enhance the company's reputation and potentially boost investor confidence. The drug's development process, involving the use of a venomous lizard's hormone, could be seen as a testament to Novo Nordisk's innovative approach to drug development.
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