Taysha Gene Therapies Presents Preclinical Data On TSHA-102 For Rett Syndrome Demonstrating Cellular Regulation Of MeCP2 Expression In Key Mouse Models At The American Society Of Gene And Cell Therapy 26th Annual Meeting
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Taysha Gene Therapies presents preclinical data on TSHA-102 for Rett syndrome, demonstrating cellular regulation of MeCP2 expression in key mouse models. The data suggests TSHA-102, engineered with miRARE technology, avoided toxic overexpression of MeCP2. Dosing of the first adult patient in the Phase 1/2 REVEAL trial is expected in Q2 2023.

May 19, 2023 | 12:05 pm
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POSITIVE IMPACT
Taysha Gene Therapies' TSHA-102 shows promising preclinical data for Rett syndrome treatment, avoiding toxic overexpression of MeCP2. First adult patient dosing in Phase 1/2 trial expected in Q2 2023.
The positive preclinical data on TSHA-102 for Rett syndrome demonstrates the potential of the miRARE technology to enable safe expression levels of MeCP2. This could lead to increased investor interest and a positive short-term impact on Taysha Gene Therapies' stock price. The dosing of the first adult patient in the Phase 1/2 REVEAL trial is expected in Q2 2023, which could further boost investor confidence.
CONFIDENCE 85
IMPORTANCE 80
RELEVANCE 100